Open AccessWhite Matter Development in Adolescence: Diffusion Tensor Imaging and Meta-Analytic Results
Author(s) -
Bart D. Peters,
Philip R. Szeszko,
Joaquim Raduà,
Toshikazu Ikuta,
Patricia Gruner,
Pamela DeRosse,
Jianping Zhang,
Antonio Giorgio,
Deqiang Qiu,
Susan F. Tapert,
Jens Bräuer,
Miya R. Asato,
Pek Lan Khong,
Anthony James,
Juan A. Gallego,
Anil K. Malhotra
Publication year - 2012
Publication title -
schizophrenia bulletin
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.823
H-Index - 190
eISSN - 1745-1701
pISSN - 0586-7614
DOI - 10.1093/schbul/sbs054
Subject(s) - fractional anisotropy , diffusion mri , white matter , superior longitudinal fasciculus , fasciculus , psychology , uncinate fasciculus , inferior longitudinal fasciculus , neuroscience , schizophrenia (object oriented programming) , audiology , medicine , magnetic resonance imaging , psychiatry , radiology
In light of the evidence for brain white matter (WM) abnormalities in schizophrenia, study of normal WM maturation in adolescence may provide critical insights relevant to the neurodevelopment of the disorder. Voxel-wise diffusion tensor imaging (DTI) studies have consistently demonstrated increases in fractional anisotropy (FA), a putative measure of WM integrity, from childhood into adolescence. However, the WM tracts that show FA increases have been variable across studies. Here, we aimed to assess which WM tracts show the most pronounced changes across adolescence.
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