Anti-Toxoplasma gondii Antibodies in Patients With Schizophrenia--Preliminary Findings in a Turkish Sample | Zendy

Zafer Çetınkaya | Zendy; S. Yazar | Zendy; Ömer Geçici | Zendy; Mustafa Namlı | Zendy

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Anti-Toxoplasma gondii Antibodies in Patients With Schizophrenia--Preliminary Findings in a Turkish Sample

Author(s) -

Zafer Çetınkaya,

S. Yazar,

Ömer Geçici,

Mustafa Namlı

Publication year - 2007

Publication title -

schizophrenia bulletin

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.823

H-Index - 190

eISSN - 1745-1707

pISSN - 0586-7614

DOI - 10.1093/schbul/sbm021

Subject(s) - toxoplasma gondii , schizophrenia (object oriented programming) , toxoplasmosis , etiology , antibody , immunology , psychiatry , medicine , autoantibody

Schizophrenia is a serious neuropsychiatric disease of uncertain etiology. We investigated the seropositivity rate for anti-Toxoplasma IgG and IgM antibodies by enzyme-linked immunosorbent assay (ELISA) in patients with schizophrenia to ascertain a possible relationship between Toxoplasma gondii and schizophrenia. We selected 100 patients with schizophrenia, 50 with depressive disorder, and 50 healthy volunteers to investigate the seropositivity rate of anti-Toxoplasma antibodies by ELISA. The seropositivity rate for anti-Toxoplasma IgG antibodies among schizophrenia patients (66%) was significantly higher than among patients with depressive disorder or healthy volunteers (P < .01). Thus, there might be a causal relationship between toxoplasmosis and the etiology of schizophrenia.

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