Monoamine Oxidase in Schizophrenia: An Overview | Zendy

Robert Wyatt | Zendy; Steven G. Potkin | Zendy; T. Peter Bridge | Zendy; Bruce H. Phelps | Zendy; C. David Wise | Zendy

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Monoamine Oxidase in Schizophrenia: An Overview

Author(s) -

Robert Wyatt,

Steven G. Potkin,

T. Peter Bridge,

Bruce H. Phelps,

C. David Wise

Publication year - 1980

Publication title -

schizophrenia bulletin

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.823

H-Index - 190

eISSN - 1745-1707

pISSN - 0586-7614

DOI - 10.1093/schbul/6.2.199

Subject(s) - monoamine oxidase , schizophrenia (object oriented programming) , etiology , psychiatry , monoamine neurotransmitter , platelet , psychology , medicine , clinical psychology , enzyme , biochemistry , chemistry , serotonin , receptor

A brief history and summary of studies designed to elucidate the role of monoamine oxidase (MAO) in schizophrenia are presented. The majority of these studies have reported a decrease in the platelet enzyme activity of chronic schizophrenic patients when compared to controls. Difficulties encountered when comparing MAO activity measured in different patient populations are also considered. Finally, the significance of decreased platelet MAO activity is discussed with respect to its possible etiological role in some forms of schizophrenia.

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