Open AccessSexual Dimorphism, Brain Morphology, and Schizophrenia
Author(s) -
Richard Lewine,
Lawrence R. Gulley,
S. Craig Risch,
R.D. Jewart,
JeffreyL. Houpt
Publication year - 1990
Publication title -
schizophrenia bulletin
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.823
H-Index - 190
eISSN - 1745-1701
pISSN - 0586-7614
DOI - 10.1093/schbul/16.2.195
Subject(s) - sexual dimorphism , brain morphometry , schizophrenia (object oriented programming) , morphology (biology) , ontogeny , context (archaeology) , sex characteristics , psychology , neuropsychology , neuroscience , biology , cognition , zoology , medicine , psychiatry , magnetic resonance imaging , endocrinology , paleontology , radiology
The study of sexual dimorphism in brain morphology may help delineate subtypes of schizophrenia based, in part, on sex; yield insight into the relationship between brain structure and behavior; and provide a neurodevelopmental context for studying the ontogenesis of schizophrenia. Preliminary findings from an ongoing study of sex differences in brain morphology and neuropsychological performance in schizophrenia suggest that schizophrenic males are characterized by multiple morphological deviations; this may represent an extreme form of normal sexual dimorphism in brain morphology. The role of brain morphology deviation in the ontogenesis of schizophrenia is discussed.