Open AccessCytokines in systemic juvenile idiopathic arthritis and haemophagocytic lymphohistiocytosis: tipping the balance between interleukin-18 and interferon-γ
Author(s) -
Karen Put,
Anneleen Avau,
Ellen Brisse,
Tania Mitera,
Stéphanie Put,
Paul Proost,
Brigitte Bader-Meunier,
René Westhovens,
Benoı̂t J. Van den Eynde,
Ciriana Orabona,
Francesca Fallarino,
Lien De Somer,
Thomas Tousseyn,
Pierre Quartier,
Carine Wouters,
Patrick Matthys
Publication year - 2015
Publication title -
rheumatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.957
H-Index - 173
eISSN - 1462-0332
pISSN - 1462-0324
DOI - 10.1093/rheumatology/keu524
Subject(s) - medicine , immunology , hemophagocytic lymphohistiocytosis , juvenile , interleukin , arthritis , balance (ability) , interferon γ , cytokine , interferon gamma , physical therapy , disease , biology , genetics
To study the role of IFN-γ in the pathogenesis of systemic JIA (sJIA) and haemophagocytic lymphohistiocytosis (HLH) by searching for an IFN-γ profile, and to assess its relationship with other cytokines.