The challenge to improve the response of biomaterials to the physiological environment | Zendy

Nicholas A. Peppas | Zendy; John R. Clegg | Zendy

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The challenge to improve the response of biomaterials to the physiological environment

Author(s) -

Nicholas A. Peppas,

John R. Clegg

Publication year - 2016

Publication title -

regenerative biomaterials

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.166

H-Index - 25

ISSN - 2056-3426

DOI - 10.1093/rb/rbw012

Subject(s) - biocompatible material , nanotechnology , drug delivery , regenerative medicine , computer science , biomedical engineering , chemistry , materials science , engineering , biochemistry , cell

New applications of biomaterials often require advanced structures containing synthetic and natural components that are tuned to provide properties unique to a specific application. We discuss how structural characteristics of biomaterials, especially hydrophilic ones, can be used in conjunction with non-ideal thermodynamics to develop advanced medical systems. We show a number of examples of biocompatible, intelligent biomaterials that can be used for organ replacement, biosensors, precise drug delivery over days or weeks, and regenerative medicine.

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