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The Quest toward limb regeneration: a regenerative engineering approach
Author(s) -
Cato T. Laurencin,
Lakshmi S. Nair
Publication year - 2016
Publication title -
regenerative biomaterials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.166
H-Index - 25
ISSN - 2056-3426
DOI - 10.1093/rb/rbw002
Subject(s) - regeneration (biology) , holy grail , regenerative medicine , computer science , tissue engineering , engineering , stem cell , biomedical engineering , biology , genetics , world wide web , microbiology and biotechnology
The Holy Grail to address the clinical grand challenge of human limb loss is to develop innovative strategies to regrow the amputated limb. The remarkable advances in the scientific understanding of regeneration, stem cell science, material science and engineering, physics and novel surgical approaches in the past few decades have provided a regenerative tool box to face this grand challenge and address the limitations of human wound healing. Here we discuss the convergence approach put forward by the field of Regenerative Engineering to use the regenerative tool box to design and develop novel translational strategies to limb regeneration.

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