Open AccessCan Beta-Endorphin Be Used as a Biomarker for Chronic Low Back Pain? A Meta-analysis of Randomized Controlled Trials
Author(s) -
Ho Yong Choi,
Chang-Hyun Lee
Publication year - 2018
Publication title -
pain medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.893
H-Index - 97
eISSN - 1526-4637
pISSN - 1526-2375
DOI - 10.1093/pm/pny186
Subject(s) - medicine , randomized controlled trial , meta analysis , biomarker , chronic pain , beta endorphin , physical therapy , biochemistry , chemistry
Chronic low back pain (CLBP) is usually quantified using the visual analog scale (VAS). However, the VAS is a subjective measure and prone to reporting bias, therefore making it difficult to differentiate patients with true pain from those seeking to obtain secondary gain. This study aimed to evaluate the feasibility of using plasma β-endorphin as an objective biomarker for CLBP.
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