From Mechanism to Cure: Renewing the Goal to Eliminate the Disease of Pain | Zendy

Theodore J. Price | Zendy; Michael S. Gold | Zendy

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From Mechanism to Cure: Renewing the Goal to Eliminate the Disease of Pain

Author(s) -

Theodore J. Price,

Michael S. Gold

Publication year - 2017

Publication title -

pain medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.893

H-Index - 97

eISSN - 1526-4637

pISSN - 1526-2375

DOI - 10.1093/pm/pnx108

Subject(s) - medicine , mechanism (biology) , disease , pain medicine , intensive care medicine , physical therapy , physical medicine and rehabilitation , psychiatry , epistemology , anesthesiology , philosophy

Persistent pain causes untold misery worldwide and is a leading cause of disability. Despite its astonishing prevalence, pain is undertreated, at least in part because existing therapeutics are ineffective or cause intolerable side effects. In this review, we cover new findings about the neurobiology of pain and argue that all but the most transient forms of pain needed to avoid tissue damage should be approached as a disease where a cure can be the goal of all treatment plans, even if attaining this goal is not yet always possible.

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