Risk Factors for Upper Gastrointestinal Bleeding in Patients Taking Selective COX-2 Inhibitors: A Nationwide Population-Based Cohort Study
Author(s) -
XiHsuan Lin,
Shih-Hao Young,
JiingChyuan Luo,
YenLing Peng,
PingHsien Chen,
ChungChi Lin,
WeiMing Chen,
MingChih Hou,
FaYauh Lee
Publication year - 2017
Publication title -
pain medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.893
H-Index - 97
eISSN - 1526-4637
pISSN - 1526-2375
DOI - 10.1093/pm/pnx097
Subject(s) - medicine , proportional hazards model , cohort study , cohort , upper gastrointestinal bleeding , population , emergency medicine , environmental health , endoscopy
Cyclooxygenase-2 inhibitors (coxibs) are associated with less upper gastrointestinal bleeding (UGIB) than traditional nonsteroidal anti-inflammatory drugs (tNSAIDs). However, they also increase the risk of UGIB in high-risk patients. We aimed to identify the risk factors of UGIB in coxibs users.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom