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Risk Factors for Upper Gastrointestinal Bleeding in Patients Taking Selective COX-2 Inhibitors: A Nationwide Population-Based Cohort Study
Author(s) -
XiHsuan Lin,
Shih-Hao Young,
JiingChyuan Luo,
YenLing Peng,
PingHsien Chen,
ChungChi Lin,
WeiMing Chen,
MingChih Hou,
FaYauh Lee
Publication year - 2017
Publication title -
pain medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.893
H-Index - 97
eISSN - 1526-4637
pISSN - 1526-2375
DOI - 10.1093/pm/pnx097
Subject(s) - medicine , proportional hazards model , cohort study , cohort , upper gastrointestinal bleeding , population , emergency medicine , environmental health , endoscopy
Cyclooxygenase-2 inhibitors (coxibs) are associated with less upper gastrointestinal bleeding (UGIB) than traditional nonsteroidal anti-inflammatory drugs (tNSAIDs). However, they also increase the risk of UGIB in high-risk patients. We aimed to identify the risk factors of UGIB in coxibs users.

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