Open AccessIntravenous Lidocaine Alleviates the Pain of Propofol Injection by Local Anesthetic and Central Analgesic Effects
Author(s) -
Jibin Xing,
Ling Liang,
Shaoli Zhou,
Chenfang Luo,
Jun Cai,
Ziqing Hei
Publication year - 2017
Publication title -
pain medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.893
H-Index - 97
eISSN - 1526-4637
pISSN - 1526-2375
DOI - 10.1093/pm/pnx070
Subject(s) - lidocaine , medicine , propofol , anesthesia , local anesthetic , saline , vein , anesthetic , analgesic , surgery
Lidocaine alleviates propofol injection pain. However, whether lidocaine works through a local anesthetic effect at the site of intravenous injection or through a systemic effect on the central nervous system remains unknown. This study aimed to determine the pain-alleviating mechanism of lidocaine.
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