Central Sensitization Is Modulated Following Trigger Point Anesthetization in Patients with Chronic Pain from Whiplash Trauma. A Double-Blind, Placebo-Controlled, Crossover Study | Zendy

N Åke Nyström | Zendy; Michael Freeman | Zendy

Open Access

Central Sensitization Is Modulated Following Trigger Point Anesthetization in Patients with Chronic Pain from Whiplash Trauma. A Double-Blind, Placebo-Controlled, Crossover Study

Author(s) -

N Åke Nyström,

Michael Freeman

Publication year - 2017

Publication title -

pain medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.893

H-Index - 97

eISSN - 1526-4637

pISSN - 1526-2375

DOI - 10.1093/pm/pnx014

Subject(s) - medicine , whiplash , visual analogue scale , anesthesia , crossover study , chronic pain , local anesthetic , placebo , physical therapy , nociception , myalgia , trapezius muscle , physical medicine and rehabilitation , electromyography , poison control , alternative medicine , receptor , environmental health , pathology

Central sensitization (CS) with low peripheral pain thresholds (PPTs) is a common finding among patients with chronic pain after whiplash (CPWI). While it has been proposed that myofascial myofascial trigger points (MTrPs) may act as modulators of central sensitization, previously reported findings are conflicting and inconclusive. The present study was designed to investigate immediate responsiveness of CS to alterations in nociceptive input.

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