Pain Modulation and Autonomic Function: The Effect of Clonidine
Author(s) -
Hadas NahmanAverbuch,
Lior Dayan,
Elliot Sprecher,
Uri Hochberg,
Silviu Brill,
David Yarnitsky,
Giris Jacob
Publication year - 2016
Publication title -
pain medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.893
H-Index - 97
eISSN - 1526-4637
pISSN - 1526-2375
DOI - 10.1093/pm/pnv102
Subject(s) - clonidine , anesthesia , placebo , analgesic , medicine , heart rate , anxiety , tonic (physiology) , heart rate variability , psychology , blood pressure , alternative medicine , pathology , psychiatry
The α2-agonist clonidine is an analgesic agent, whose yet uncertain action may involve either increase in pain modulation efficiency, change in autonomic function, and/or decrease in anxiety level. The present study aimed to examine the effect of oral clonidine on pain perception in healthy subjects in order to reveal its mode of action.
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