Correlation Between DNA Methylation of TRPA1 and Chronic Pain States in Human Whole Blood Cells | Zendy

Norihiko Sukenaga | Zendy; Yasuko Ikeda-Miyagawa | Zendy; Daisuke Tanada | Zendy; Takashi Tunetoh | Zendy; Susumu Nakano | Zendy; Takae Inui | Zendy; Kazumi Satoh | Zendy; Hiroai Okutani | Zendy; Koichi Noguchi | Zendy; Munetaka Hirose | Zendy

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Correlation Between DNA Methylation of TRPA1 and Chronic Pain States in Human Whole Blood Cells

Author(s) -

Norihiko Sukenaga,

Yasuko Ikeda-Miyagawa,

Daisuke Tanada,

Takashi Tunetoh,

Susumu Nakano,

Takae Inui,

Kazumi Satoh,

Hiroai Okutani,

Koichi Noguchi,

Munetaka Hirose

Publication year - 2016

Publication title -

pain medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.893

H-Index - 97

eISSN - 1526-4637

pISSN - 1526-2375

DOI - 10.1093/pm/pnv088

Subject(s) - ankyrin , chronic pain , dna methylation , medicine , transient receptor potential channel , peripheral blood , whole blood , immune system , methylation , dna , receptor , immunology , bioinformatics , biology , psychiatry , genetics , gene , gene expression

Neuro-immune interactions with functional changes in the peripheral blood cells including changes in the transient receptor potential ankyrin 1 (TRPA1) appear to play a pivotal role in the development of chronic pain in humans. The aim of this study was to examine the association between TRPA1 DNA methylation in whole blood cells and the pain states in chronic pain patients.

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