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Salivary Alpha-Amylase Correlates with Subjective Heat Pain Perception
Author(s) -
Amrei Wittwer,
Peter Krummenacher,
Roberto La Marca,
Ulrike Ehlert,
Gerd Folkers
Publication year - 2016
Publication title -
pain medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.893
H-Index - 97
eISSN - 1526-4637
pISSN - 1526-2375
DOI - 10.1093/pm/pnv085
Subject(s) - saliva , medicine , visual analogue scale , biomarker , perception , quantitative sensory testing , audiology , physical therapy , anesthesia , psychology , sensory system , neuroscience , biochemistry , chemistry
Self-reports of pain are important for an adequate therapy. This is a problem with patients and infants who are restricted in providing an accurate verbal estimation of their pain. Reliable, real-time, economical, and non-invasive physiological correlates might contribute to a more comprehensive description of pain. Salivary alpha-amylase constitutes one candidate biomarker, which reflects predominantly sympathetic nervous system alterations under stressful conditions and can be measured non-invasively. The current study investigated the effects of acute heat pain on salivary alpha-amylase activity.

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