Transcranial Direct Current Stimulation (tDCS) Targeting Left Dorsolateral Prefrontal Cortex Modulates Task-Induced Acute Pain in Healthy Volunteers | Zendy

Timothy Y. Mariano | Zendy; Mascha van ‘t WoutFrank | Zendy; Sarah L. Garnaat | Zendy; Steven A. Rasmussen | Zendy; Benjamin D. Greenberg | Zendy

Open Access

Transcranial Direct Current Stimulation (tDCS) Targeting Left Dorsolateral Prefrontal Cortex Modulates Task-Induced Acute Pain in Healthy Volunteers

Author(s) -

Timothy Y. Mariano,

Mascha van ‘t WoutFrank,

Sarah L. Garnaat,

Steven A. Rasmussen,

Benjamin D. Greenberg

Publication year - 2015

Publication title -

pain medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.893

H-Index - 97

eISSN - 1526-4637

pISSN - 1526-2375

DOI - 10.1093/pm/pnv042

Subject(s) - transcranial direct current stimulation , dorsolateral prefrontal cortex , medicine , prefrontal cortex , neuroscience , dorsolateral , stimulation , neuromodulation , physical medicine and rehabilitation , task (project management) , psychology , cognition , management , economics

Current chronic pain treatments target nociception rather than affective "suffering" and its associated functional and psychiatric comorbidities. The left dorsolateral prefrontal cortex (DLPFC) has been implicated in affective, cognitive, and attentional aspects of pain and is a primary target of neuromodulation for affective disorders. Transcranial direct current stimulation (tDCS) can non-invasively modulate cortical activity. The present study tests whether anodal tDCS targeting the left DLPFC will increase tolerability of acute painful stimuli vs cathodal tDCS.

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