Open AccessIdentification of an F-Box Protein that Negatively Regulates Pi Starvation Responses
Author(s) -
Zhihui Chen,
Gareth I. Jenkins,
Hugh G. Nimmo
Publication year - 2008
Publication title -
plant and cell physiology/plant and cell physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.975
H-Index - 152
eISSN - 1471-9053
pISSN - 0032-0781
DOI - 10.1093/pcp/pcn157
Subject(s) - regulator , mutant , arabidopsis , gene , proteolysis , negative regulator , pi , biology , f box protein , genetics , microbiology and biotechnology , ubiquitin , biochemistry , ubiquitin ligase , enzyme
The Arabidopsis gene At5g21040 encodes a protein containing both WD40 and F-box motifs, termed FBX2. A T-DNA insertional mutant in this gene was obtained. Analysis of this mutant line showed that FBX2 is a negative regulator of several P(i) starvation responses. FBX2 interacts with BHLH32, another negative regulator of P(i) starvation responses. We suggest that FBX2 may be part of an SCF-like complex that recruits BHLH32 and its partners, potentially targeting the latter for proteolysis.