Ectopic Expression of the NtSET1 Histone Methyltransferase Inhibits Cell Expansion, and Affects Cell Division and Differentiation in Tobacco Plants | Zendy

WenHui Shen | Zendy; Denise Meyer | Zendy

Open Access

Ectopic Expression of the NtSET1 Histone Methyltransferase Inhibits Cell Expansion, and Affects Cell Division and Differentiation in Tobacco Plants

Author(s) -

WenHui Shen,

Denise Meyer

Publication year - 2004

Publication title -

plant and cell physiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.975

H-Index - 152

eISSN - 1471-9053

pISSN - 0032-0781

DOI - 10.1093/pcp/pch184

Subject(s) - ectopic expression , epigenetics , histone , histone methyltransferase , histone h3 , cell division , biology , methyltransferase , microbiology and biotechnology , methylation , cell growth , cell , genetics , gene

The tobacco NtSET1 gene encodes a member of the SUV39H family of histone methyltransferases. Ectopic expression of NtSET1 causes an increase in methylated histone H3 lysine 9 and abnormal chromosome segregation in tobacco suspension cells, and inhibits tobacco plant growth. Here we show that the inhibition of plant growth was caused by reduced cell expansion as well as by abnormal cell division and differentiation. We found that deletion of the C-terminally located catalytic domain of the protein abolished the ectopic effects of NtSET1 on plant growth. Our results indicate that histone H3 lysine 9 methylation is a critical mark of epigenetic control for plant development.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research