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Can the personalized medicine approach contribute in controlling tuberculosis in general and India in particular?
Author(s) -
Nikhat Khan,
Aparup Das
Publication year - 2020
Publication title -
precision clinical medicine
Language(s) - English
Resource type - Journals
eISSN - 2096-5303
pISSN - 2516-1571
DOI - 10.1093/pcmedi/pbaa021
Subject(s) - tuberculosis , isoniazid , personalized medicine , mycobacterium tuberculosis , medicine , principal (computer security) , precision medicine , intensive care medicine , traditional medicine , biology , bioinformatics , pathology , computer science , operating system
Poor drug compliance and drug-resistant Mycobacterium tuberculosis are the two principal obstacles in controlling tuberculosis (TB) in endemic regions including India, which has contributed the most to global TB burden. We argue here that a personalized medicine approach, to start with the N-acetyl transferase-2–isoniazid (NAT2–INH) model, could be a step forward in dealing with both these limitations in controlling TB in India.

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