Epigenetics: What does it mean for paediatric practice?
Author(s) -
Judith G. Hall
Publication year - 2014
Publication title -
paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.55
H-Index - 43
eISSN - 1918-1485
pISSN - 1205-7088
DOI - 10.1093/pch/19.1.27
Subject(s) - epigenetics , humanities , biology , ethnology , microbiology and biotechnology , genetics , gene , philosophy , sociology
'Epigenetics' involves the study of gene expression and the environmental exposures that influence expression. In paediatrics, it is recognized that different physiological and developmental stages of the young individual are affected by both genetic control and environmental influence. It appears that changes in gene expression - not changes in the DNA itself - can be passed on from one generation to another. The importance for paediatricians is recognizing disorders involving epigenetics, recording events during childhood that could affect epigenetic control of gene expression, and being aware of new therapies as they become available. Paediatricians need to be able to recognize the relevant risk factors.
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