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Therapeutic strategies, including a high surgical ligation rate, for patent ductus arteriosus closure in extremely premature infants in a North American centre
Author(s) -
Gregory P. Moore,
Sarah Lawrence,
Gyaandeo Maharajh,
Amanda Sumner,
Isabelle Gaboury,
Nick Barrowman,
Brigitte Lemyre
Publication year - 2012
Publication title -
paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.55
H-Index - 43
eISSN - 1918-1485
pISSN - 1205-7088
DOI - 10.1093/pch/17.4.e26
Subject(s) - medicine , ductus arteriosus , ligation , gestational age , population , mechanical ventilation , mortality rate , anesthesia , pediatrics , surgery , pregnancy , genetics , environmental health , biology
To document the rate of surgical ligation of a patent ductus arteriosus (PDA) in extremely premature infants who had received more than one course of indomethacin. Outcomes were compared among three subgroups (ligation, further indomethacin and no further treatment) of infants who received at least one course of indomethacin, and between two subgroups (one course of indomethacin and more than one course) among infants who underwent ligation.

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