Neurologic symptoms as the only manifestation of B12deficiency in a young patient with normal hematocrit, MCV, peripheral blood smear and homocysteine levels

B deficiency is associated with several neurological manifestations. It is well documented that neurologic symptoms due to B deficiency may sometimes present in the absence of anemia. However, in most cases there are several indicating factors like megaloblastic changes in complete blood count, hypersegmentated neutrophils or macroovalocytes in peripheral blood smear and abnormal homocysteine levels. In this report, we describe a case of a 32-year-old man with neurological symptomatology as the only manifestation of B deficiency with normal hematocrit, mean cell volume, peripheral blood smear and homocysteine levels. All the above emphasize the point that patients with neurologic symptoms must be screened for B deficiency even in the absence of any laboratory evidence.