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‘Unique does not mean impossible: infant presenting with complicated course of ulceroglandular tularemia.’
Author(s) -
Karolina Miącz,
Jakub Śledź,
Marek W. Karwacki
Publication year - 2021
Publication title -
oxford medical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.169
H-Index - 9
ISSN - 2053-8855
DOI - 10.1093/omcr/omab086
Subject(s) - tularemia , medicine , hepatosplenomegaly , francisella tularensis , mononucleosis , cervical lymphadenopathy , dermatology , axillary lymphadenopathy , cat scratch disease , differential diagnosis , bartonella , lymphoma , tick , anemia , disease , pathology , immunology , virology , virus , biology , biochemistry , cancer , virulence , breast cancer , gene
Tularemia is a disease caused by Francisella tularensis—gram-negative coccobacillus. The ulceroglandular type characterized by skin ulcers and painful regional adenopathy is recognized as the most common. A 1-year-old patient was admitted with severe normocytic anemia, high fever and hepatosplenomegaly. A nonspecific lesion in the axillary region with a homogenous nodal reaction was found, combined with a history of a tick-bite in the pectoral muscle. Primary differentiation included leukemia, lymphoma, mononucleosis, borrelial lymphoma and simple abscess. All of the above were excluded. A further search for diagnosis focused on tick-borne diseases: TIBOLa or anaplasmosis. The ulceroglandular tularemia was eventually confirmed serologically. Besides the fact that tularemia is a rare diagnosis nowadays, it is still necessary to include this disease in the differentiation of a nonresolving tick-bite abscess with lymphadenopathy. Diagnostic vigilance is the key to effective treatment because other obvious symptoms such as severe anemia might delay the diagnosis.

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