Open AccessNon-Hodgkin lymphoma of bone of the femur and humerus: a case report and review of the literature
Author(s) -
Alex Mremi,
Jeremia J Pyuza,
Bilal Ahmad,
Alice A Andongolile,
Adnan Sadiq,
James J. Yahaya,
Károly Szuhai,
Pancras C.W. Hogendoorn
Publication year - 2021
Publication title -
oxford medical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.169
H-Index - 9
ISSN - 2053-8855
DOI - 10.1093/omcr/omab024
Subject(s) - medicine , humerus , lymphoma , soft tissue , femur , lesion , pathology , thigh , pathological , radiology , pathologic fracture , surgery
Lymphoma of bone is a rare neoplasm composed of malignant lymphoid cells, producing a tumefactive lesion within bone. We report a 13-year-old male who presented with progressively increasing swellings at the right shoulder and right mid-thigh for one month. Radiological images revealed lytic destructive lesions associated with soft tissue masses in both sites and a pathological fracture on the right humerus. The patient had no significant medical history. Histological, immunohistochemical and fluorescent in-situ hybridization assessment of biopsies from the lesions confirmed the diagnosis of primary non-Hodgkin lymphoma of bone. Unfortunately, due to coronavirus disease 2019 outbreak, the patient was unable to follow-up treatment and died shortly after establishment of the diagnosis. Delay in diagnosis and treatment is of serious concern when it comes to improve the prognosis of patients with this disease.