Genetic Determinants of Trehalose Utilization Are Not Associated With Severe Clostridium difficile Infection Outcome | Zendy

Katie Saund | Zendy; Krishna Rao | Zendy; Vincent B. Young | Zendy; Evan S. Snitkin | Zendy

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Genetic Determinants of Trehalose Utilization Are Not Associated With Severe Clostridium difficile Infection Outcome

Author(s) -

Katie Saund,

Krishna Rao,

Vincent B. Young,

Evan S. Snitkin

Publication year - 2020

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofz548

Subject(s) - clostridium difficile , context (archaeology) , c difficile , medicine , microbiology and biotechnology , virulence , trehalose , clostridium infections , clostridium , antibiotics , bacteria , biology , gene , genetics , paleontology , biochemistry

In a case-control study of patients with infection, we found no statistically significant association between the presence of trehalose utilization variants in infecting strains and development of severe infection outcome. These results do not support trehalose utilization conferring enhanced virulence in the context of human infections.

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