The differential characteristics between severe fever with thrombocytopenia syndrome and hemorrhagic fever with renal syndrome in the endemic regions | Zendy

QingBin Lu | Zendy; Li Hao | Zendy; Fachun Jiang | Zendy; Lingling Mao | Zendy; Xuesheng Liu | Zendy; Ning Wang | Zendy; Yong-Yun Zhou | Zendy; Ke Dai | Zendy; ZhenDong Yang | Zendy; Liyan Dong | Zendy; Ning Cui | Zendy; XiaoAi Zhang | Zendy; ShaoFei Zhang | Zendy; PanHe Zhang | Zendy; LiQun Fang | Zendy; Wei Liu | Zendy

Open Access

The differential characteristics between severe fever with thrombocytopenia syndrome and hemorrhagic fever with renal syndrome in the endemic regions

Author(s) -

QingBin Lu,

Li Hao,

Fachun Jiang,

Lingling Mao,

Xuesheng Liu,

Ning Wang,

Yong-Yun Zhou,

Ke Dai,

ZhenDong Yang,

Liyan Dong,

Ning Cui,

XiaoAi Zhang,

ShaoFei Zhang,

PanHe Zhang,

LiQun Fang,

Wei Liu

Publication year - 2019

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofz477

Subject(s) - medicine , diarrhea , lymph , severe fever with thrombocytopenia syndrome , white blood cell , high fever , confidence interval , fever of unknown origin , immunology , gastroenterology , pathology , virus

The misdiagnosis between severe fever with thrombocytopenia syndrome and hemorrhagic fever with renal syndrome were identified in endemic regions for both diseases. A model based on age, mouse/tick contact in recent one month, clinical characteristics including blush, low back pain, diarrhea, enlarged lymph nodes, and white blood cell count, yielded a high area under the curve of 0.985 (95% confidence interval, 0.979-0.992), enabling an effective differentiation between two diseases.

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