Changes in the Fungal Marker β-D-Glucan After Antiretroviral Therapy and Association With Adiposity | Zendy

Sahera DirajlalFargo | Zendy; Carlee Moser | Zendy; Katherine Rodríguez | Zendy; Vanessa El Kamari | Zendy; Nicholas Funderburg | Zendy; Emily Bowman | Zendy; Todd T. Brown | Zendy; Peter W. Hunt | Zendy; Judith S. Currier | Zendy; Grace A. McComsey | Zendy

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Changes in the Fungal Marker β-D-Glucan After Antiretroviral Therapy and Association With Adiposity

Author(s) -

Sahera DirajlalFargo,

Carlee Moser,

Katherine Rodríguez,

Vanessa El Kamari,

Nicholas Funderburg,

Emily Bowman,

Todd T. Brown,

Peter W. Hunt,

Judith S. Currier,

Grace A. McComsey

Publication year - 2019

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofz434

Subject(s) - medicine , antiretroviral therapy , human immunodeficiency virus (hiv) , association (psychology) , gerontology , family medicine , viral load , philosophy , epistemology

In treatment-naïve participants initiating antiretroviral therapy (ART) with TDF/FTC and either RAL or ATV/r, DRV/r, BDG, a marker of fungal translocation, increased similarly in all arms over 96 weeks. This may represent continued intestinal damage during ART and resulting fungal translocation. Higher BDG was associated with larger fat gains on ART.

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