Successful Treatment of Mycobacterium chelonae Keratitis Within a Corneal Transplant Using Intrastromal Amikacin Injections—A Case Report Demonstrating the Fundamental Principles and Challenges of Infective Keratitis Management and Novel Therapeutic Approaches
Author(s) -
Nancy Louisa Merridew,
Ravinder Singh Phagura,
Edward Anderson,
Louise Cooley,
Graeme A Pollock,
Belinda McEwan,
Paul James McCartney,
MohamadAli Trad
Publication year - 2019
Publication title -
open forum infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.546
H-Index - 35
ISSN - 2328-8957
DOI - 10.1093/ofid/ofz340
Subject(s) - mycobacterium chelonae , medicine , keratitis , amikacin , ophthalmology , mycobacterium abscessus , optometry , microbiology and biotechnology , mycobacterium , antimicrobial , pathology , biology , tuberculosis
keratitis is rare and difficult to treat. This is the first known case worldwide of effective treatment using intrastromal amikacin injections in a corneal transplant recipient who had metastatic breast cancer. The challenges and principles of management, applicable to other causes of infective keratitis, are reviewed.
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