HIV Coinfection Predicts Failure of Ledipasvir/Sofosbuvir in Treatment-Naïve Noncirrhotic Patients With HCV Genotype 1 | Zendy

Juan Berenguer | Zendy; José Luís Calleja | Zendy; Marisa Montes | Zendy; Ángela Gil | Zendy; Ana Moreno | Zendy; Rafael Bañares | Zendy; Teresa AldámizEchevarría | Zendy; Agustı́n Albillos | Zendy; María Jesús Téllez | Zendy; Antonio Olveira | Zendy; Lourdes Domínguez | Zendy; Inmaculada Fernández | Zendy; Javier GarcíaSamaniego | Zendy; Benjamín Polo Lorduy | Zendy; Beatriz Álvarez | Zendy; Pablo Ryan | Zendy; Jesús Barrio | Zendy; M. J. Devesa | Zendy; Laura Benítez | Zendy; Ignacio de los Santos | Zendy; Luisa García Buey | Zendy; José Sanz | Zendy; Elvira Poves | Zendy; Juan Emilio Losa | Zendy; Conrado Fernández-Rodrı́guez | Zendy; Inmaculada Jarrín | Zendy; María José Calvo | Zendy; Juan GonzálezGarcía | Zendy

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HIV Coinfection Predicts Failure of Ledipasvir/Sofosbuvir in Treatment-Naïve Noncirrhotic Patients With HCV Genotype 1

Author(s) -

Juan Berenguer,

José Luís Calleja,

Marisa Montes,

Ángela Gil,

Ana Moreno,

Rafael Bañares,

Teresa AldámizEchevarría,

Agustı́n Albillos,

María Jesús Téllez,

Antonio Olveira,

Lourdes Domínguez,

Inmaculada Fernández,

Javier GarcíaSamaniego,

Benjamín Polo Lorduy,

Beatriz Álvarez,

Pablo Ryan,

Jesús Barrio,

M. J. Devesa,

Laura Benítez,

Ignacio de los Santos,

Luisa García Buey,

José Sanz,

Elvira Poves,

Juan Emilio Losa,

Conrado Fernández-Rodrı́guez,

Inmaculada Jarrín,

María José Calvo,

Juan GonzálezGarcía

Publication year - 2019

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofz214

Subject(s) - medicine , ledipasvir , sofosbuvir , hepatitis c virus , coinfection , hepatitis c , odds ratio , gastroenterology , confidence interval , human immunodeficiency virus (hiv) , immunology , ribavirin , virus

The results of this large prospective study analyzing outcomes for LDV/SOF against HCV G1 in treatment-naïve noncirrhotic patients suggest that HIV infection is a predictor of treatment failure in patients with chronic hepatitis C.

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