Rabbit Antithymocyte Globulin Causes Blastomyces and Histoplasma Antigenemia
Author(s) -
Amrit Kaur,
Michael Eberlein,
Julia KlesneyTait,
Michelle Durkin,
L. Joseph Wheat,
Kiran Gajurel
Publication year - 2019
Publication title -
open forum infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.546
H-Index - 35
ISSN - 2328-8957
DOI - 10.1093/ofid/ofz165
Subject(s) - blastomyces , medicine , histoplasma , blastomyces dermatitidis , globulin , immunology , histoplasma capsulatum , microbiology and biotechnology , virology , histoplasmosis , blastomycosis , biology
Rabbit antithymocyte globulin (rATG) is known to yield false-positive antigenemia. The fourth generation MiraVista antigen assay was modified to block this effect (MiraVista Diagnostics, Indianapolis, Indiana). We report a case of rATG-induced false-positive and antigenemia in a lung transplant recipient despite modifications of these antigen assays.
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