Long-term Follow-up Reveals High Posttreatment Mortality Rate Among Patients With Extensively Drug-Resistant Tuberculosis in the Country of Georgia | Zendy

Melanie Frank | Zendy; Natalia Adamashvili | Zendy; Nino Lomtadze | Zendy; Eka Kokhreidze | Zendy; Zaza Avaliani | Zendy; Russell R. Kempker | Zendy; Henry M. Blumberg | Zendy

Open Access

Long-term Follow-up Reveals High Posttreatment Mortality Rate Among Patients With Extensively Drug-Resistant Tuberculosis in the Country of Georgia

Author(s) -

Melanie Frank,

Natalia Adamashvili,

Nino Lomtadze,

Eka Kokhreidze,

Zaza Avaliani,

Russell R. Kempker,

Henry M. Blumberg

Publication year - 2019

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofz152

Subject(s) - medicine , tuberculosis , extensively drug resistant tuberculosis , term (time) , gerontology , mortality rate , pediatrics , intensive care medicine , demography , mycobacterium tuberculosis , pathology , physics , quantum mechanics , sociology

The overall mortality rate and specifically the posttreatment mortality rate were high among patients with XDR-TB. Patients with an unfavorable end-of-treatment outcome had an increased risk of death during follow-up. Our findings highlight the need for improved adherence, better-tolerated and shorter therapies, and enhanced posttreatment surveillance among patients treated for XDR-TB.

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