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Human Immunodeficiency Virus (HIV) 2 Superinfection in a Patient Receiving Antiretroviral Therapy With Longstanding HIV-1 Viral Load Suppression
Author(s) -
Filipa Ceia,
André SilvaPinto,
Ana Cláudia Carvalho,
Carmela Piñeiro,
Joaquim Soares,
Rosário Serrão,
António Sarmento
Publication year - 2019
Publication title -
open forum infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.546
H-Index - 35
ISSN - 2328-8957
DOI - 10.1093/ofid/ofz063
Subject(s) - superinfection , medicine , viral load , human immunodeficiency virus (hiv) , virology , antiretroviral therapy , sida , virus , immunology , drug resistance , lentivirus , viral disease , biology , microbiology and biotechnology
Dual human immunodeficiency virus (HIV) 1 and HIV-2 superinfections are rare but challenging. A HIV-1-infected patient receiving effective antiretroviral therapy was investigated for a severe CD4 cell count decline. HIV-2 superinfection was diagnosed and genotypic test revealed mutations conferring resistance to most drug class, limiting options for treatment.

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