Treatment of Posaconazole-Induced Peripheral Neuropathy With Methylprednisolone and Magnesium Infusions: A Case Report | Zendy

Sadia Hussain | Zendy; Susan E. Nissen | Zendy; Steven M. Holland | Zendy; Paola Sandroni | Zendy; Michail S. Lionakis | Zendy

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Treatment of Posaconazole-Induced Peripheral Neuropathy With Methylprednisolone and Magnesium Infusions: A Case Report

Author(s) -

Sadia Hussain,

Susan E. Nissen,

Steven M. Holland,

Paola Sandroni,

Michail S. Lionakis

Publication year - 2019

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofz031

Subject(s) - medicine , posaconazole , methylprednisolone , tolerability , peripheral neuropathy , adverse effect , anesthesia , magnesium , surgery , pharmacology , dermatology , endocrinology , antifungal , voriconazole , materials science , metallurgy , diabetes mellitus

The tolerability of long-term posaconazole use remains poorly defined. We present a patient who developed peripheral neuropathy following long-term exposure to the tablet formulation of posaconazole, which was treated with methylprednisolone and magnesium infusions. The potential role of methylprednisolone and magnesium infusions in managing this potentially irreversible triazole-associated complication requires further study.

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