Effect of a Single Standard Dose (150–200 μg/kg) of Ivermectin onLoa loaMicrofilaremia: Systematic Review and Meta-analysis | Zendy

Sébastien D. S. Pion | Zendy; Jules Brice TchatchuengMbougua | Zendy; Cédric B. Chesnais | Zendy; Joseph Kamgno | Zendy; Jacques Gardon | Zendy; JeanPhilippe Chippaux | Zendy; Stéphane Ranque | Zendy; Jean-Christophe Ernould | Zendy; André Garcia | Zendy; Michel Boussinesq | Zendy

Open Access

Effect of a Single Standard Dose (150–200 μg/kg) of Ivermectin onLoa loaMicrofilaremia: Systematic Review and Meta-analysis

Author(s) -

Sébastien D. S. Pion,

Jules Brice TchatchuengMbougua,

Cédric B. Chesnais,

Joseph Kamgno,

Jacques Gardon,

JeanPhilippe Chippaux,

Stéphane Ranque,

Jean-Christophe Ernould,

André Garcia,

Michel Boussinesq

Publication year - 2019

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofz019

Subject(s) - loa loa , ivermectin , onchocerca volvulus , onchocerciasis , medicine , adverse effect , parasitemia , microfilaria , mass drug administration , anthelmintic , veterinary medicine , immunology , filariasis , environmental health , malaria , helminths , population , plasmodium falciparum

A single dose of IVM is very effective at substantially reducing MFD for at least a year, irrespective of the initial level of parasitemia. Individuals treated with IVM are probably not any more at risk of severe adverse events when retreated 1 year later.

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