Progression of Baseline Electrocardiogram Abnormalities in Chagas Patients Undergoing Antitrypanosomal Treatment | Zendy

Jonathan Soverow | Zendy; Salvador Hernández | Zendy; Daniel R. Sanchez | Zendy; Colin Forsyth | Zendy; Carmen A. Flores | Zendy; Gracia Viana | Zendy; Sheba Meymandi | Zendy

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Progression of Baseline Electrocardiogram Abnormalities in Chagas Patients Undergoing Antitrypanosomal Treatment

Author(s) -

Jonathan Soverow,

Salvador Hernández,

Daniel R. Sanchez,

Colin Forsyth,

Carmen A. Flores,

Gracia Viana,

Sheba Meymandi

Publication year - 2019

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofz012

Subject(s) - medicine , chagas disease , baseline (sea) , cardiology , virology , geology , oceanography

Over an average follow-up of 3.9 years, treated patients with normal baseline ECGs did not have significant changes during a course of treatment; however, those with baseline abnormal ECGs had significant progression of their conduction system disease despite treatment, and those without treatment also experienced a progression of ECG disease. These preliminary results suggest that Chagas patients with normal ejection fraction and normal ECG may benefit the most from antitrypanosomal treatment.

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