Clinical, Histopathological, and Virological Evaluation of 203 Patients With a Clinical Diagnosis of Molluscum Contagiosum | Zendy

Katarina Trčko | Zendy; Lea Hošnjak | Zendy; Blanka Kušar | Zendy; Tomaž Mark Zorec | Zendy; Boštjan J. Kocjan | Zendy; Miljenko Križmarić | Zendy; Katja Seme | Zendy; Jovan Miljković | Zendy; Boštjan Luzar | Zendy; Mario Poljak | Zendy

Open Access

Clinical, Histopathological, and Virological Evaluation of 203 Patients With a Clinical Diagnosis of Molluscum Contagiosum

Author(s) -

Katarina Trčko,

Lea Hošnjak,

Blanka Kušar,

Tomaž Mark Zorec,

Boštjan J. Kocjan,

Miljenko Križmarić,

Katja Seme,

Jovan Miljković,

Boštjan Luzar,

Mario Poljak

Publication year - 2018

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofy298

Subject(s) - molluscum contagiosum , medicine , dermatology , genital warts , pathology , histopathological examination , clinical diagnosis , cancer , pediatrics , cervical cancer

Molluscum contagiosum (MC) manifests as small, umbilicated papules caused by the molluscum contagiosum virus (MCV). The extent of clinical misdiagnosis of MC is unknown. Combined clinical, histopathological, and virological evaluation of 203 consecutive patients with clinical diagnosis of MC treated at a university hospital during a 5-year period showed the correct clinical diagnosis in 188 of 203 (92.6%) patients. All 15 clinically misdiagnosed MC lesions were histopathologically and virologically confirmed as either common or anogenital warts caused by different human papillomaviruses. The MCV1/MCV2 subtypes ratio was 1.54:1, and the distribution of MCV subtypes differed across patients' age and anatomical location of lesions.

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