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Salvage Debridement, Antibiotics and Implant Retention (“DAIR”) With Local Injection of a Selected Cocktail of Bacteriophages: Is It an Option for an Elderly Patient With Relapsing Staphylococcus aureus Prosthetic-Joint Infection?
Author(s) -
Tristan Ferry,
Gilles Leboucher,
Cindy Fèvre,
Yannick Herry,
Anne Conrad,
Jérôme Josse,
Cécile Batailler,
Christian Chidiac,
Mathieu Médina,
Sébastien Lustıg,
Frédéric Laurent,
Florent Valour,
Thomas Perpoint,
A. Boibieux,
F. Biron,
Patrick Miailhes,
Florence Ader,
Agathe Becker,
Sandrine Roux,
Claire Triffault-Fillit,
Alexie Bosch,
Fatiha Daoud,
Johanna Lippman,
E. Braun,
Elvire Servien,
Romain Gaillard,
Antoine Schneider,
Stanislas Gunst,
Michel-Henry Fessy,
JeanLuc Besse,
Anthony Viste,
Philippe Chaudier,
Cyril Courtin,
Lucie Louboutin,
Sébastien Martres,
Franck Trouillet,
Cédric Barrey,
Emmanuel Jouanneau,
Timothée Jacquesson,
Ali Mojallal,
Fabien Boucher,
Hristo Shipkov,
Joseph Château,
Frédéric Aubrun,
Mikhail Dziadzko,
Caroline Macabéo,
L. Béraud,
Camille Kolenda,
Céline Dupieux,
Fabien Craighero,
Loïc Boussel,
JeanBaptiste Pialat,
Isabelle Morelec,
M. Janier,
Francesco Giammarile,
Michel Tod,
MarieClaude Gagnieu,
Sylvain Goutelle,
Béatrice Grisi,
Cédric Dananché,
Eugénie Mabrut
Publication year - 2018
Publication title -
open forum infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.546
H-Index - 35
ISSN - 2328-8957
DOI - 10.1093/ofid/ofy269
Subject(s) - medicine , debridement (dental) , staphylococcus aureus , antibiotics , surgery , implant , staphylococcal infections , intravenous antibiotics , microbiology and biotechnology , bacteria , genetics , biology
Local injection of a bacteriophages mix during debridement, antibiotics and implant retention (“DAIR”) was performed to treat a relapsing Staphylococcus aureus chronic prosthetic joint infection (PJI). This salvage treatment was safe and associated with a clinical success. Scientific evaluation of the potential clinical benefit of bacteriophages as antibiofilm treatment in PJI is now feasible and required.

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