Multiplicity of Infection Is a Poor Predictor of Village-Level Plasmodium vivax and P. falciparum Population Prevalence in the Southwest Pacific | Zendy

Cristian Koepfli | Zendy; Andreea Waltmann | Zendy; Maria OmeKaius | Zendy; Leanne J. Robinson | Zendy; Ivo Müeller | Zendy

Open Access

Multiplicity of Infection Is a Poor Predictor of Village-Level Plasmodium vivax and P. falciparum Population Prevalence in the Southwest Pacific

Author(s) -

Cristian Koepfli,

Andreea Waltmann,

Maria OmeKaius,

Leanne J. Robinson,

Ivo Müeller

Publication year - 2018

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofy240

Subject(s) - medicine , plasmodium falciparum , plasmodium vivax , malaria , demography , vivax malaria , population , virology , immunology , environmental health , sociology

Across 8101 individuals in 46 villages, the proportion of spp. multiple clone infections (0%-53.8%) did not reflect prevalence by quantitative polymerase chain reaction (qPCR; 1.9%-38.4%), except for in Solomon Islands ( < .001). Thus this parameter was not informative to identify transmission foci. In contrast, prevalence by microscopy and qPCR correlated well.

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