Cryptococcal Meningitis and Tuberculous Meningitis Co-infection in HIV-Infected Ugandan Adults | Zendy

Jayne Ellis | Zendy; Fiona V Cresswell | Zendy; Joshua Rhein | Zendy; Kenneth Ssebambulidde | Zendy; David R. Boulware | Zendy

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Cryptococcal Meningitis and Tuberculous Meningitis Co-infection in HIV-Infected Ugandan Adults

Author(s) -

Jayne Ellis,

Fiona V Cresswell,

Joshua Rhein,

Kenneth Ssebambulidde,

David R. Boulware

Publication year - 2018

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofy193

Subject(s) - medicine , cryptococcal meningitis , meningitis , tuberculous meningitis , human immunodeficiency virus (hiv) , viral meningitis , immunology , virology , bacterial meningitis , pediatrics , viral disease

We report 5 HIV-infected Ugandan adults with cryptococcal and tuberculous (TB) meningitis co-infection. All unmasked meningitis occurred within 5 weeks of starting HIV therapy. Xpert MTB/RIF Ultra facilitated prompt diagnosis; however, 60% in-hospital mortality occurred. TB meningitis coinfection prevalence was 0.8% (5/586) among cryptococcal meningitis, 2 during second cryptococcal episodes.

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