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No Impact of Probiotics to Reduce Clostridium difficile Infection in Hospitalized Patients: A Real-world Experience
Author(s) -
Maggie Box,
Kristine Ortwine,
Miguel Goicoechea
Publication year - 2018
Publication title -
open forum infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.546
H-Index - 35
ISSN - 2328-8957
DOI - 10.1093/ofid/ofy192
Subject(s) - medicine , clostridium difficile , incidence (geometry) , probiotic , antibiotics , c difficile , lactobacillus , gastroenterology , intensive care medicine , microbiology and biotechnology , bacteria , physics , genetics , optics , biology
We assessed the effectiveness of a Lactobacillus probiotic on rates of health care facility–onset Clostridium difficile infection (HO-CDI) in patients receiving antibiotics. A total of 1576 patients were evaluated. There was no difference in the HO-CDI incidence between those who received probiotics and those who did not (1.8% vs 0.9%; P = .16).

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