Prevalence and Transmission Dynamics of HIV-1 Transmitted Drug Resistance in a Southeastern Cohort | Zendy

Sara N. Levintow | Zendy; Nwora Lance Okeke | Zendy; Stéphane Hué | Zendy; Laura Mkumba | Zendy; Arti Virkud | Zendy; Sonia Napravnik | Zendy; Joseph Sebastian | Zendy; William C. Miller | Zendy; Joseph J. Eron | Zendy; Ann M. Dennis | Zendy

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Prevalence and Transmission Dynamics of HIV-1 Transmitted Drug Resistance in a Southeastern Cohort

Author(s) -

Sara N. Levintow,

Nwora Lance Okeke,

Stéphane Hué,

Laura Mkumba,

Arti Virkud,

Sonia Napravnik,

Joseph Sebastian,

William C. Miller,

Joseph J. Eron,

Ann M. Dennis

Publication year - 2018

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofy178

Subject(s) - medicine , human immunodeficiency virus (hiv) , cohort , transmission (telecommunications) , drug resistance , virology , cohort study , hiv drug resistance , drug , intravenous drug , antiretroviral therapy , viral load , viral disease , pharmacology , microbiology and biotechnology , telecommunications , computer science , biology

Moderate TDR prevalence persists in North Carolina, predominantly driven by NNRTI resistance. Most TDR cases were identified in transmission clusters, signifying multiple local transmission networks and TDR circulation among ART-naïve persons. Transmitted drug resistance surveillance can detect transmission networks and identify patients for enhanced services to promote early treatment.

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