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HIV Testing After a First Positive Rapid Diagnostic Test: A Role for Nucleic Acid Testing?
Author(s) -
Anne M. Neilan,
Jennifer Cohn,
JeanFrançois Lemaire,
Emma Sacks,
Rebecca Alban,
Kenneth A. Freedberg,
Rochelle P. Walensky,
Andrea Ciaranello
Publication year - 2018
Publication title -
open forum infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.546
H-Index - 35
ISSN - 2328-8957
DOI - 10.1093/ofid/ofy170
Subject(s) - point of care testing , medicine , human immunodeficiency virus (hiv) , nucleic acid , nucleic acid amplification tests , test strategy , diagnostic test , test (biology) , reliability engineering , machine learning , computer science , virology , immunology , pediatrics , biology , programming language , paleontology , engineering , biochemistry , software , chlamydia trachomatis
We developed an open-access, Excel-based model simulating currently recommended and alternative algorithms for adult HIV testing as a preliminary investigation of trade-offs between accuracy and costs. Despite higher costs, simpler HIV testing algorithms incorporating point of care nucleic acid testing may improve outcomes and thus merit additional research and field testing.

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