The Cefazolin Inoculum Effect Is Associated With Increased Mortality in Methicillin-Susceptible Staphylococcus aureus Bacteremia | Zendy

William R. Miller | Zendy; Carlos Seas | Zendy; Lina P Carvajal | Zendy; Lorena Díaz | Zendy; Aura M Echeverri | Zendy; Carolina Ferro | Zendy; Rafael Ríos | Zendy; Paola Porras | Zendy; Carlos M. Luna | Zendy; Eduardo Gotuzzo | Zendy; José M. Munita | Zendy; Esteban C. Nannini | Zendy; Cesar Cárcamo | Zendy; Jinnethe Reyes | Zendy; César A. Arias | Zendy

Open Access

The Cefazolin Inoculum Effect Is Associated With Increased Mortality in Methicillin-Susceptible Staphylococcus aureus Bacteremia

Author(s) -

William R. Miller,

Carlos Seas,

Lina P Carvajal,

Lorena Díaz,

Aura M Echeverri,

Carolina Ferro,

Rafael Ríos,

Paola Porras,

Carlos M. Luna,

Eduardo Gotuzzo,

José M. Munita,

Esteban C. Nannini,

Cesar Cárcamo,

Jinnethe Reyes,

César A. Arias

Publication year - 2018

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofy123

Subject(s) - cefazolin , bacteremia , medicine , staphylococcus aureus , cephalosporin , endocarditis , nafcillin , staphylococcal infections , confidence interval , antibiotics , microbiology and biotechnology , penicillin , biology , bacteria , genetics

In patients with MSSA bacteremia where cephalosporins are used as firstline therapy, the CzIE was associated with increased 30-day mortality. Clinicians should be cautious when using cefazolin as firstline therapy for these infections.

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