Performance of TEM-PCR vs Culture for Bacterial Identification in Pediatric Musculoskeletal Infections | Zendy

James B. Wood | Zendy; Cheryl L. Sesler | Zendy; Donald Stalons | Zendy; Elena L. Grigorenko | Zendy; Jonathan G. Schoenecker | Zendy; C. Buddy Creech | Zendy; Isaac Thomsen | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Performance of TEM-PCR vs Culture for Bacterial Identification in Pediatric Musculoskeletal Infections

Author(s) -

James B. Wood,

Cheryl L. Sesler,

Donald Stalons,

Elena L. Grigorenko,

Jonathan G. Schoenecker,

C. Buddy Creech,

Isaac Thomsen

Publication year - 2018

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofy119

Subject(s) - medicine , pathogen , multiplex polymerase chain reaction , microbiological culture , polymerase chain reaction , antibiotics , identification (biology) , antimicrobial , pathogenic organism , microbiology and biotechnology , virology , immunology , bacteria , biology , genetics , gene , botany

Improved diagnostics are needed for children with musculoskeletal infections (MSKIs). We assessed the performance of target-enriched multiplex polymerase chain reaction (TEM-PCR) in children with MSKI. TEM-PCR was concordant with culture in pathogen identification and antibiotic susceptibility testing, while increasing the overall yield of pathogen detection. This technology has the potential to inform judicious antimicrobial use early in the disease course.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research