Asymptomatic Prenatal Zika Virus Infection and Congenital Zika Syndrome | Zendy

Enny S. Paixão | Zendy; Wei Yee Leong | Zendy; Laura C. Rodrigues | Zendy; Annelies WilderSmith | Zendy

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Asymptomatic Prenatal Zika Virus Infection and Congenital Zika Syndrome

Author(s) -

Enny S. Paixão,

Wei Yee Leong,

Laura C. Rodrigues,

Annelies WilderSmith

Publication year - 2018

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofy073

Subject(s) - zika virus , medicine , asymptomatic , retrospective cohort study , pediatrics , prospective cohort study , microcephaly , virology , virus

To investigate to what extent asymptomatic vs symptomatic prenatal Zika virus infections contribute to birth defects, we identified 3 prospective and 8 retrospective studies. The ratio varied greatly in the retrospective studies, most likely due to recruitment and recall bias. The prospective studies revealed a ratio of 1:1 for asymptomatic vs symptomatic maternal Zika infections resulting in adverse fetal outcomes.

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