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Successful Treatment of Cerebral Toxoplasmosis Using Pyrimethamine Oral Solution Compounded From Inexpensive Bulk Powder
Author(s) -
Hayley A Hodgson,
Taeyong Sim,
Hemil Gonzalez,
Mariam Aziz,
Yoona Rhee,
Paul Lewis,
Neel Jhobalia,
Beth Shields,
Sheila K Wang
Publication year - 2018
Publication title -
open forum infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.546
H-Index - 35
ISSN - 2328-8957
DOI - 10.1093/ofid/ofy055
Subject(s) - pyrimethamine , medicine , toxoplasmosis , toxoplasma gondii , sulfadiazine , suspension (topology) , intensive care medicine , pediatrics , virology , antibiotics , immunology , malaria , microbiology and biotechnology , plasmodium falciparum , antibody , mathematics , homotopy , pure mathematics , biology
A price increase of pyrimethamine tablets in the United States has made the life-saving drug difficult to acquire for hospitalized patients who need it most. We report the successful use of a pyrimethamine oral suspension compounded from an economical bulk powder in a patient with acute toxoplasmic encephalitis.

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