A Novel Single-Nucleotide Polymorphism Loop Mediated Isothermal Amplification Assay for Detection of Artemisinin-Resistant Plasmodium falciparum Malaria | Zendy

Abu Naser Mohon | Zendy; Didier Ménard | Zendy; Mohammad Shafiul Alam | Zendy; Kevin Perera | Zendy; Dylan R. Pillai | Zendy

Open Access

A Novel Single-Nucleotide Polymorphism Loop Mediated Isothermal Amplification Assay for Detection of Artemisinin-Resistant Plasmodium falciparum Malaria

Author(s) -

Abu Naser Mohon,

Didier Ménard,

Mohammad Shafiul Alam,

Kevin Perera,

Dylan R. Pillai

Publication year - 2018

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofy011

Subject(s) - plasmodium falciparum , artemisinin , medicine , malaria , loop mediated isothermal amplification , virology , single nucleotide polymorphism , genetics , computational biology , biology , genotype , immunology , gene , dna

Single-nucleotide polymorphism LAMP can serve as a surveillance tool and guide treatment algorithms for ARM in a clinically relevant time frame, prevent unnecessary use of additional drugs that may drive additional resistance, and avoid longer treatment regimens that cause toxicity for the patient.

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