Durability of Efavirenz Compared With Boosted Protease Inhibitor-Based Regimens in Antiretroviral-Naïve Patients in the Caribbean and Central and South America
Author(s) -
Yanink Caro-Vega,
Pablo F. Belaunzarán-Zamudio,
Brenda CrabtreeRamírez,
Bryan E. Shepherd,
Beatriz Grinsztejn,
Marcelo Wolff,
Jean W. Pape,
Denis Padgett,
Eduardo Gotuzzo,
Catherine C. McGowan,
Juan SierraMadero
Publication year - 2018
Publication title -
open forum infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.546
H-Index - 35
ISSN - 2328-8957
DOI - 10.1093/ofid/ofy004
Subject(s) - efavirenz , medicine , protease inhibitor (pharmacology) , human immunodeficiency virus (hiv) , virology , antiretroviral therapy , caribbean region , viral load , latin americans , linguistics , philosophy
Durability of firstline ART was longer with EFV than with bPIs. EFV-based regimens may continue to be the preferred firstline regimen for our region in the near future due to their high efficacy, relatively low toxicity (especially at lower doses), existence of generic formulations, and affordability for national programs.
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