Decay of HIV DNA in the Reservoir and the Impact of Short Treatment Interruption in Kenyan Infants | Zendy

Mark D Pankau | Zendy; Dalton Wamalwa | Zendy; Sarah BenkiNugent | Zendy; Kenneth Tapia | Zendy; Evelyn Ngugi | Zendy; Agnes Langat | Zendy; Vincent Otieno | Zendy; Helen Moraa | Zendy; Elizabeth MalecheObimbo | Zendy; Julie Overbaugh | Zendy; Grace JohnStewart | Zendy; Dara A. Lehman | Zendy

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Decay of HIV DNA in the Reservoir and the Impact of Short Treatment Interruption in Kenyan Infants

Author(s) -

Mark D Pankau,

Dalton Wamalwa,

Sarah BenkiNugent,

Kenneth Tapia,

Evelyn Ngugi,

Agnes Langat,

Vincent Otieno,

Helen Moraa,

Elizabeth MalecheObimbo,

Julie Overbaugh,

Grace JohnStewart,

Dara A. Lehman

Publication year - 2017

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofx268

Subject(s) - medicine , kenya , human immunodeficiency virus (hiv) , virology , pediatrics , biology , ecology

We compared change in HIV reservoir DNA following continued antiretroviral therapy (ART) vs short treatment interruption (TI) in early ART-treated Kenyan infants. While HIV DNA in the reservoir decayed with continued ART, HIV DNA levels were similar to pre-TI HIV DNA reservoir levels in most children after short TI.

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