Experience with Kaposi Sarcoma Herpesvirus Inflammatory Cytokine Syndrome in a Large Urban HIV Clinic in the United States: Case Series and Literature Review | Zendy

Valeria D. Cantos | Zendy; Aley G. Kalapila | Zendy; Minh Ly Nguyen | Zendy; Marylyn Adamski | Zendy; Clifford Gunthel | Zendy

Open Access

Experience with Kaposi Sarcoma Herpesvirus Inflammatory Cytokine Syndrome in a Large Urban HIV Clinic in the United States: Case Series and Literature Review

Author(s) -

Valeria D. Cantos,

Aley G. Kalapila,

Minh Ly Nguyen,

Marylyn Adamski,

Clifford Gunthel

Publication year - 2017

Publication title -

open forum infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.546

H-Index - 35

ISSN - 2328-8957

DOI - 10.1093/ofid/ofx196

Subject(s) - medicine , human immunodeficiency virus (hiv) , virology , sarcoma , series (stratigraphy) , immunology , pathology , paleontology , biology

In 2010, a new entity, characterized by the classical signs and symptoms of Kaposi sarcoma herpesvirus–associated multicentric Castleman’s disease (KSHV-MCD) in the absence of pathologic evidence of MCD, was described in individuals living with HIV. This syndrome was named KSHV inflammatory cytokine syndrome (KICS). It carries mortality rates of up to 60%. To date, there are no standard therapies. Treatment regimens studied in clinical trials for MCD disease are used in cases of KICS.

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